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Publications

exel

Recent Publications [Proteomics, Cancer, Cholesterol Metabolism] (since 1997)

  1. Kim S, Paik YK (2008)
    "Developmental and reproductive consequences of prolonged non-aging dauer in Caenorhabditis elegans"
    Biochem Biophys Res Commun 368(3): 588-92


  2. Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Bjorling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagne P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjern©ª K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Korner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Lobke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A. (2008)
    "Human Proteinpedia enables sharing of human protein data"
    Nat. Biotechnol. 26(2): 164-7


  3. Omenn GS, Aebersold R, Paik YK (2007)
    "HUPO Plasma Proteome Project 2007 Workshop Report."
    Mol Cell Proteomics 6(12): 2252-3


  4. Cha MH, Rhim T, Kim KH, Jang AS, Paik YK, Park CS (2007)
    "Proteomic Identification of Macrophage Migration-inhibitory Factor upon Exposure to TiO2 Particles."
    Mol Cell Proteomics. 6(1): 56-63


  5. Young-Ki Paik, Eun-Young Lee, Min-Seok Kwon, Sang-Yun Cho, Hoguen Kim (2007)
    "General Overview and Introduction to Clinical Proteomics "
    Methods in Mol. Biol. (textbook) Humana Pub. Co. (in press) :


  6. Byung-Kwon Choi, Yun-Kyung Shin, Eun-Young Lee, Pan-Young Jeong, Sun-Young Kim (2007)
    "Proteomic analysis of the sterol-mediated signaling pathways in C. elegans"
    Methods in Mol. Biol. (textbook), Humana Pub. Co. (in press) :


  7. Cho SY, Lee EY, Kim HY, Kang MJ, Lee HJ, Kim H, Paik YK (2007)
    "Protein profiling of human plasma samples by two-dimensional electrophoresis"
    Methods Mol Biol 428: 57-76


  8. Paik YK, Kim H, Lee EY, Kwon MS, Cho SY (2007)
    "Overview and introduction to clinical proteomics"
    Methods Mol Biol 428: 1-32


  9. Paik YK, Jeong SK, Lee EY, Jeong PY, Shim YH (2006)
    "C. elegans : an invaluable model organism for the proteomics studies of the cholesterol-mediated signaling pathway."
    Expert Rev Proteomics 3(4): 439


  10. An S, Cho KH, Lee WS, Lee JO, Paik YK, Jeong TS (2006)
    "A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2"
    FEBS Lett. 580(11): 2741-9


  11. Byun K, Kim J, Cho SY, Hutchinson B, Yang SR, Kang KS, Cho M, Hwang K, Michikawa M, Jeon YW, Paik YK, Lee B (2006)
    "Alteration of the glutamate and GABA transporters in the hippocampus of the Niemann-Pick disease, type C mouse using proteomic analysis."
    Proteomics 6(4): 1230-6


  12. Park GW, Kwon KH, Kim JY, Lee JH, Yun SH, Kim SI, Park YM, Cho SY, Paik YK, Yoo JS (2006)
    "Human plasma proteome analysis by reversed sequence database search and molecular weight correlation based on a bacterial proteome analysis."
    Proteomics 6(4): 1121-32


  13. Shin YK, Lee HJ, Lee JS, Paik YK (2006)
    "Proteomic analysis of mammalian basic proteins by liquid-based two-dimensional column chromatography."
    Proteomics 6(4): 1143-50


  14. Yeo M, Kim DK, Park HJ, Oh TY, Kim JH, Cho SW, Paik YK, Hahm KB (2006)
    "Loss of transgelin in repeated bouts of ulcerative colitis-induced colon carcinogenesis."
    Proteomics 6(4): 1158-65


  15. Kang HJ, Koh KH, Yang E, You KT, Kim HJ, Paik YK, Kim H (2006)
    "Differentially expressed proteins in gastrointestinal stromal tumors with KIT and PDGFRA mutations."
    Proteomics 6(4): 1151-7


  16. Park YD, Jang HS, Kim SY, Ko SK, Lyou YJ, Lee DY, Paik YK, Yang JM (2006)
    "Two-dimensional electrophoretic profiling of atopic dermatitis in primary cultured keratinocytes from patients."
    Proteomcis 6(4): 1362-70


  17. Lee SH, Rhim T, Choi YS, Min JW, Kim SH, Cho SY, Paik YK, Park CS (2006)
    "Complement C3a and C4a increased in plasma of patients with aspirin-induced asthma."
    Proteomics 173(4): 370-8


  18. An S, Park YD, Paik YK, Jeong TS, Lee WS (2006)
    "Human ACAT inhibitory effects of shikonin derivatives from Lithospermum erythrorhizon."
    Bioorg Med Chem Lett. in press:


  19. Choi CB, Cho YK, Prakash KV, Jee BK, Han CW, Paik YK, Kim HY, Lee KH, Chung N, Rha HK (2006)
    "Analysis of neuron-like differentiation of human bone marrow mesenchymal stem cells."
    Biochem Biophys Res Commun. 350(1): 138-46


  20. Lee HJ, Lee EY, Kwon MS, Paik YK (2006)
    "Biomarker discovery from the plasma proteome using multidimensional fractionation proteomics"
    Curr Opin Chem Biol. 10: 42-49


  21. Omenn GS, Paik YK, Speicher D (2006)
    "The HUPO Plasma Proteome Project: a report from the Munich congress."
    Proteomics 6(1): 9-11


  22. Wilkins MR, Appel RD, Van Eyk JE, Chung MC, Gorg A, Hecker M, Huber LA, Langen H, Link AJ, Paik YK, Patterson SD, Pennington SR, Rabilloud T, Simpson RJ, Weiss W, Dunn MJ (2006)
    "Guidelines for the next 10 years of proteomics."
    Proteomics 6(1): 4-8


  23. Sang-Yun Cho, Eun-Young Lee, Young-Ki Paik (2006)
    "Proteomic profiling of plasma samples by 2-dimensional electrophoresis. "
    Methods in Mol. Biol. (textbook) Humana Pub. Co. (in press) :


  24. Omenn GS, States DJ, Adamski M, Blackwell TW, Menon R, Hermjakob H, Apweiler R, Haab BB, Simpson RJ, Eddes JS, Kapp EA, Moritz RL, Chan DW, Rai AJ, Admon A, Aebersold R, Eng J, Hancock WS, Hefta SA, Meyer H, Paik YK, Yoo JS, Ping P, Pounds J, Adkins J, Qian X, Wang R, Wasinger V, Wu CY, Zhao X, Zeng R, Archakov A, Tsugita A, Beer I, Pandey A, Pisano M, Andrews P, Tammen H, Speicher DW, Hanash SM (2005)
    "Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database."
    Proteomics 5(13): 3226-45


  25. Kim JY, Lee JH, Park GW, Cho K, Kwon KH, Park YM, Cho SY, Paik YK, Yoo JS (2005)
    "Utility of electrophoretically derived protein mass estimates as additional constraints in proteome analysis of human serum based on MS/MS analysis."
    Proteomics 5(13): 3376-85


  26. Ping P, Vondriska TM, Creighton CJ, Gandhi T, Yang Z, Menon R, Kwon MS, Cho SY, Drwal G, Kellmann M, Peri S, Suresh S, Gronborg M, Molina H, Chaerkady R, Rekha B, Shet AS, Gerszten RE, Wu H, Raftery M, Wasinger V, Schulz-Knappe P, Hanash SM, Paik YK, Hancock WS, States DJ, Omenn GS, Pandey A (2005)
    "A functional annotation of subproteomes in human plasma."
    Proteomics 5(13): 3506-19


  27. Cho SY, Lee EY, Lee JS, Kim HY, Park JM, Kwon MS, Park YK, Lee HJ, Kang MJ, Kim JY, Yoo JS, Park SJ, Cho JW, Kim HS, Paik YK (2005)
    "Efficient prefractionation of low-abundance proteins in human plasma and construction of a two-dimensional map."
    Proteomics 5(13): 3386-96


  28. Kim JH, Hwang EH, Park HJ, Paik YK, Shim YH (2005)
    "Methylation of CpG islands in the rat 7-dehydrocholesterol reductase promoter suppresses transcriptional activation."
    Mol Cells 19(2): 279-82


  29. Lee EY, Shim YH, Chitwood DJ, Hwang SB, Lee J, Paik YK. (2005)
    "Cholesterol-producing transgenic Caenorhabditis elegans lives longer due to newly acquired enhanced stress resistance"
    Biochem Biophys Res Commun. 328(4): 929-36


  30. Jeong PY, Jung M, Yim YH, Kim H, Park M, Hong E, Lee W, Kim YH, Kim K, Paik YK (2005)
    "Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone."
    Nature 433(7025): 541-545


  31. Shin KD, Lee MY, Shin DS, Lee S, Son KH, Koh S, Paik YK, Kwon BM, Han DC (2005)
    "Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation."
    J Biol Chem 280(50): 41439-48


  32. Shin YK, Kim KY, Paik YK (2005)
    "Alterations of protein expression in macrophages in response to Candida albicans infection."
    Mol Cells 20(2): 271-9


  33. Paik YK (2005)
    "KHUPO, a Vital Catalyst for Proteomics Research in Asia and the World"
    BioForum Europe 5: 14-15


  34. Kim KY, Shin YK, Park JC, Kim JH, Yang H, Han DM, Paik YK (2004)
    "Molecular cloning and biochemical characterization of Candida albicans acyl-CoA:sterol acyltransferase, a potential target of antifungal agents."
    Biochem Biophys Res Commun. 319(3): 911-9


  35. Shim YH, Bae SH, Kim JH, Kim KR, Kim CJ, Paik YK (2004)
    "A novel mutation of the human 7-dehydrocholesterol reductase gene reduces enzyme activity in patients with holoprosencephaly"
    Biochem Biophys Res Commun 315(1): 219-23


  36. Park JY, Seong JK, Paik YK (2004)
    "Proteomic analysis of diet-induced hypercholesterolemic mice."
    Proteomics 4(2): 514-23


  37. Park YD, Kim SY, Jang HS, Seo EY, Namkung JH, Park HS, Cho SY, Paik YK, Yang JM (2004)
    "Towards a proteomic analysis of atopic dermatitis: a two-dimensional-polyacrylamide gel electrophoresis/mass spectrometric analysis of cultured patient-derived fibroblasts."
    Proteomics 4(11): 3446-3455


  38. Park B, Jeong SK, Lee WS, Seong JK, Paik YK (2004)
    "A simple pattern classification method for alcohol-responsive proteins that are differentially expressed in mouse brain."
    Proteomics 4(11): 3369-75


  39. Li LS, Kim H, Rhee H, Kim SH, Shin DH, Chung KY, Park KS, Paik YK, Chang J, Kim H (2004)
    "Proteomic analysis distinguishes basaloid carcinoma as a distinct subtype of nonsmall cell lung carcinoma."
    Proteomics 4(11): 3394-400


  40. Yeo M, Park HK, Kim DK, Cho SW, Kim YS, Cho SY, Paik YK, Hahm KB (2004)
    "Restoration of heat shock protein70 suppresses gastric mucosal inducible nitric oxide synthase expression induced by Helicobacter pylori."
    Proteomics 4(11): 3335-42


  41. Park B, Oh SH, Seong JK, Paik YK (2004)
    "A strain-specific alteration of proteomic expression in mouse liver fructose 1,6-bisphosphatase isoforms by alcohol"
    Proteomics 4(11): 3413-21


  42. Young-Ki Paik (2004)
    "Disease Proteomics in Korea"
    Proteomics 4(11): 3297-3298


  43. Bae SH, Harris AG, Hains PG, Chen H, Garfin DE, Hazell SL, Paik YK, Walsh BJ, Cordwell SJ, (2003)
    "Strategies for the enrichment and identification of basic proteins in proteome projects"
    Proteomics 3(5): 569-79


  44. Choi YR, Kim H, Kang HJ, Kim NG, Kim JJ, Park KS, Paik YK, Kim HO, Kim H (2003)
    "Overexpression of high mobility group box 1 in gastrointestinal stromal tumors with KIT mutation."
    Cancer Res. 63(9): 2188-93


  45. Mackintosh JA, Choi HY, Bae SH, Veal DA, Bell PJ, Ferrari BC, Van Dyk DD, Verrills NM, Paik YK, Karuso P (2003)
    "A fluorescent natural product for ultra sensitive detection of proteins in one-dimensional and two-dimensional gel electrophoresis."
    Proteomics 3(12): 2273-88


  46. Young-Ki Paik (2003)
    "A new horizon of proteomics in Korea. "
    Proteomics 3(12):


  47. Choi BK, Cho YM, Bae SH, Zoubaulis CC, Paik YK (2003)
    "Single-step perfusion chromatography with a throughput potential for enhanced peptide detection by matrix-assisted laser desorption/ ionization-mass spectrometry."
    Proteomics 3(10): 1955-61


  48. Cho YM, Bae SH, Choi BK, Cho SY, Song CW, Yoo JK, Paik YK (2003)
    "Differential expression of the liver proteome in senescence accelerated mice"
    Proteomics 3(10): 1883-94


  49. Cho KH, An S, Lee WS, Paik YK, Kim YK, Jeong TS (2003)
    "Mass-production of human ACAT-1 and ACAT-2 to screen isoform-specific inhibitor: a different substrate specificity and inhibitory regulation"
    Biochem Biophys Res Commun. 309(4): 864-72


  50. Choi BK, Chitwood DJ, Paik YK. (2003)
    "Proteomic Changes during Disturbance of Cholesterol Metabolism by Azacoprostane Treatment in Caenorhabditis elegans."
    Mol Cell Proteomics. 2(10): 1086-1095


  51. Cho SY, Park KS, Shim JE, Kwon MS, Joo KH, Lee WS, Chang J, Kim H, Chung HC, Kim HO, Paik YK. (2002)
    "An integrated proteome database for two-dimensional electrophoresis data analysis and laboratory information management system."
    Proteomics 2(9): 1104-13


  52. Chang J, Kim NG, Piao Z, Park C, Park KS, Paik YK, Lee WJ, Kim BR, Kim H., (2002)
    "Assessment of chromosomal losses and gains in hepatocellular carcinoma."
    Cancer Letter. 182(2): 193-202